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Beilstein J. Org. Chem. 2007, 3, No. 30, doi:10.1186/1860-5397-3-30
Graphical Abstract
Scheme 1: Syntheses of (-)-209B, (-)-231C, (-)-233D, and (-)-235B".
Scheme 2: Syntheses of (-)-221I and (-)-7 (an epimer of 193E).
Figure 1: Inhibitory effect of (-)-231C on ACh-induced currents in X. laevis oocytes expressing recombinant n...
Figure 2: Inhibitory effect of (-)-221I on ACh-induced currents in X. laevis oocytes expressing recombinant n...
Figure 3: Inhibitory effect of (-)-epi-193E on ACh-induced currents in X. laevis oocytes expressing recombina...
Beilstein J. Org. Chem. 2007, 3, No. 29, doi:10.1186/1860-5397-3-29
Figure 1: Representative examples of 5,8-Disubstituted Indolizidines.
Figure 2: Synthetic Strategies to 5,8-Disubstituted Indolizidines from Chiral Building Blocks (1,2).
Scheme 1: Construction of tri-substituted piperidine ring systems (7, 8).
Figure 3: Stereochemical Course of Key Michael-type Conjugate Addition Reaction of 6.
Scheme 2: Synthesis of common lactam-type chiral building blocks (1, 2).
Scheme 3: Synthesis of (-)-203A and (-)-205A.
Scheme 4: Synthesis of (-)-219F.